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Medchemexpress LLC Protac BCR-ABL1 ligand 1 | 2489876-34-6 | 99.2% | C17H12F3N3O2 | 10MG

Supplier: Medchemexpress LLC HY13029710MG
PROTAC BCR-ABL1 ligand 1 (GMB-475) is a small-molecule PROTAC ligand that allosterically binds BCR-ABL1 and recruits the Von Hippel-Lindau (VHL) E3 ligase, promoting ubiquitination and proteasomal degradation of BCR-ABL1. It is provided as research reagent material in both solid and solution forms for biochemical and cell-based studies.
- Allosterically binds BCR-ABL1 and recruits VHL E3 ligase.
- Promotes ubiquitination and proteasomal degradation of BCR-ABL1.
- Chemical formula C17H12F3N3O2, molecular weight 347.29 g·mol-1.
- Purity ≥ 99.17% (HPLC reported).
- Available as solid (5-100 mg) and 10 mM solution in DMSO.
- Intended for research use only.
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