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Medchemexpress LLC Protac BCR-ABL1 ligand 1 | 2489876-34-6 | 99.2% | C17H12F3N3O2 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13029710MG

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PROTAC BCR-ABL1 ligand 1 (GMB-475) is a small-molecule PROTAC ligand that allosterically binds BCR-ABL1 and recruits the Von Hippel-Lindau (VHL) E3 ligase, promoting ubiquitination and proteasomal degradation of BCR-ABL1. It is provided as research reagent material in both solid and solution forms for biochemical and cell-based studies.

  • Allosterically binds BCR-ABL1 and recruits VHL E3 ligase.
  • Promotes ubiquitination and proteasomal degradation of BCR-ABL1.
  • Chemical formula C17H12F3N3O2, molecular weight 347.29 g·mol-1.
  • Purity ≥ 99.17% (HPLC reported).
  • Available as solid (5-100 mg) and 10 mM solution in DMSO.
  • Intended for research use only.

Catalog No. 50-002-60648


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