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Medchemexpress LLC Protac BET degrader-1 | 2093386-22-0 | 99.4% | 871.90 g/mol | C44H45N11O9 | 1 ML
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Supplier:  Medchemexpress LLC HY10363310MM 1ML

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PROTAC BET Degrader-1 is a proteolysis-targeting chimera that links a Cereblon ligand to a BET-family ligand to promote ubiquitination and proteasomal degradation of BET proteins BRD2, BRD3, and BRD4. It is used in biochemical and cellular assays to investigate BET protein degradation and downstream epigenetic effects.

  • Induces selective degradation of BRD2, BRD3, and BRD4 at low nanomolar concentrations.
  • Provided as a 10 mM solution in DMSO, 1 mL vial.
  • High purity (99.4% by LCMS).
  • Molecular formula C44H45N11O9; molecular weight 871.90 g/mol.
  • Storage: powder -20°C for long term; in solvent -80°C recommended.

Catalog No. 50-002-46831


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