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Medchemexpress LLC PROTAC BET Degrader-10 | 1957234-97-7 | 99.4% | 783.29 | 50 MG
Supplier: Medchemexpress LLC HY11271850MG
PROTAC BET Degrader-10 (dBET37) is a potent BET protein BRD4 degrader. It is connected by ligands for Cereblon and BRD4, and has a DC50 of 49 nM. This product is for research use only and not sold to patients. PROTACs use two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase and the other targets the protein of interest. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Potent BET protein BRD4 degrader
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- Connected by ligands for Cereblon and BRD4
- DC50 of 49 nM
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