Medchemexpress LLC PROTAC EGFR degrader 11 | 3034244-71-5 | 99.2% | 991.61 | 1 MG

Supplier:  Medchemexpress LLC HY1616331MG

PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 <100 nM. It binds CRBN-DDB1 with a Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.

• PROTAC degrader for epidermal growth factor receptor (EGFR).
• DC50 <100 nM.
• Binds CRBN-DDB1 with a Ki of 36 nM.
• Degrades EGFR, focal adhesion kinase (FAK), and RSK1.
• Inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.

Catalog No. 50-003-92900