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Medchemexpress LLC PROTAC EGFR degrader 7 (diTFA) | 3033297-59-2 | 99.19% | 1064.98 | 5 MG

Supplier: Medchemexpress LLC HY147858A5MG
PROTAC EGFR degrader 7 (compound 13b) is a potent and selective CRBN-recruiting PROTAC EGFRL858R/T790M degrader, with a DC50 of 13.2 nM. It inhibits NCI-H1975 cells proliferation, with an IC50 of 46.82 nM.
- Significantly induces apoptosis and G2/M phase arrest in NCI-H1975 cell.
- Shows antitumor activity.
- Can be used for non-small cell lung cancer (NSCLC) research.
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