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Medchemexpress LLC PROTAC ERα Degrader-4 | 2521299-80-7 | 99.1% | 1074.23 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1492955MG

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PROTAC ERα Degrader-4 (Compound ZD12) is a highly potent and selective PROTAC ERα degrader with a Ki of 5.08 μM. It contains OBHSAs, linker, and E3 ligase ligands, demonstrating excellent cell inhibitory and ERα degradation activity against Tamoxifen-sensitive and -resistant ER+ breast cancer (BC) cells and ERα-mutated BC cells. It can induce apoptosis and is suitable for cancer research.

  • Highly potent and selective ERα degrader
  • Contains OBHSAs, linker, and E3 ligase ligands
  • Exhibits excellent cell inhibitory and ERα degradation activity
  • Effective against Tamoxifen-sensitive and -resistant ER+ breast cancer (BC) cells
  • Effective against ERα-mutated BC cells
  • Induces apoptosis
  • Suitable for cancer research

Catalog No. 50-003-59537


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