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Medchemexpress LLC PROTAC KRAS G12C degrader-1 | 2984236-79-3 | 99.15% | 917.47 | 50 MG
Supplier: Medchemexpress LLC HY13918650MG
PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C PROTAC degrader. It induces CRBN/KRASG12C dimerization and degrades GFP-KRASG12C in reporter cells. This compound is for research use only.
- Engages CRBN in cells
- Binds KRASG12C in vitro
- Induces CRBN/KRASG12C dimerization
- Degrades GFP-KRASG12C in reporter cells in a CRBN-dependent manner
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