Medchemexpress LLC Protac α-synuclein degrader 3 | 2412273-77-7 | ≥98.0% | C51H68N6O11S2 | 10MG

Supplier:  Medchemexpress LLC HY13600110MG

PROTAC α-synuclein degrader 3 is a proteolysis-targeting chimera developed for research applications to induce ubiquitination and proteasomal degradation of α-synuclein, useful in Parkinson's disease model studies. It has documented in vitro and in vivo formulation solubility and recommended storage conditions for stable handling.

• Selective α-synuclein degrader that promotes ubiquitination and proteasomal degradation.
• Demonstrated to reduce α-synuclein levels (≈65% reduction at 1 μM).
• Soluble in DMSO at 100 mg/mL with ultrasonic assistance.
• Formulatable for in vivo dosing in multiple vehicle systems at ≥2.5 mg/mL.
• Stable when stored as powder at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
• For research use only; not intended for clinical or therapeutic use.

Catalog No. 50-002-59210