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Medchemexpress LLC Protac α-synuclein degrader 5 | 2781922-42-5 | 100.0% | 767.78 g/mol | C39H41N7O10 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY15502110MG

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PROTAC α-synuclein degrader 5 is a small-molecule PROTAC designed to selectively target and promote degradation of α-synuclein aggregates in cellular models. Supplied as a high-purity solid for preclinical research, it shows dose-dependent activity in fibril-seeding assays and is formulated for in vitro and in vivo use.

  • Selective degradation of α-synuclein aggregates (DC50 ≈ 7.5 μM, Dmax 89%).
  • Demonstrated reduction of aggregates within 48 hours in PFF seeding cell models.
  • High-purity solid suitable for biochemical and cellular assays.
  • High solubility in DMSO for in vitro applications (≥100 mg/mL).
  • Compatible with in vivo formulation protocols and frozen storage for stability.

Catalog No. 50-002-87472


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