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Medchemexpress LLC Protectin D1 | 660430-03-5 | 99.1% | 50 UG
Supplier: Medchemexpress LLC HY13041350UG
Protectin D1, also known as Neuroprotectin D1 (NPD1), is a bioactive product derived from docosahexaenoic acid, produced by neuronal cells. It acts as a specialized pro-resolving mediator, demonstrating effective in vivo pro-resolving activity in various human disease models. It is also an inhibitor of NALP3 inflammasomes and regulates the PI3K/AKT and HIF-1α signaling pathways.
- Exerts anti-inflammatory effects by reducing reactive oxygen species (ROS) levels
- Inhibits the expression of NALP3, ASC, and Caspase-1
- Decreases the release of pro-inflammatory cytokines IL-1β and IL-18
- Enhances miRNA-210 expression
- Activates the PI3K/AKT signaling pathway
- Provides cardioprotective effects
- Shows promise for research in cardiovascular diseases and inflammatory disorders
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