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Apexbio Technology LLC Protionamide 14222-60-7 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B20165.1
Protionamide is a thiophene-derived antibacterial compound that inhibits the synthesis of mycolic acids a major component of the mycobacterial cell wall Through disruption of mycolic acid biosynthesis it interferes with cell wall integrity exhibiting antibacterial activity against pathogenic mycobacteria Protionamide is commonly employed in research involving Mycobacterium tuberculosis and Mycobacterium leprae primarily for investigating molecular mechanisms underlying drug resistance and cell wall biosynthesis pathways In laboratory experiments this compound is frequently utilized in vitro for cultivation assays antimicrobial screening and studies on synergistic effects when combined with other antimycobacterial agents It demonstrates reported IC50 values in the micromolar range dependent on experimental conditions and mycobacterial strains used
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