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Medchemexpress LLC Protoporphyrin IX | 553-12-8 | MFCD00151109 | 98.0% | 100 MG
Supplier: Medchemexpress LLC HYB1247R100MG
Protoporphyrin IX is an endogenous metabolite and a final intermediate in the heme biosynthetic pathway. It functions as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also acts as a photosensitizer that undergoes photobleaching from light irradiation. It accumulates in tumor cells after administration of 5-aminolevulinic acid (5-ALA).
- Endogenous metabolite and final intermediate in heme biosynthetic pathway
- Functions as a radiation sensitizer
- Enhances ROS generation even in hypoxic conditions
- Induces DNA damage
- Acts as a photosensitizer that undergoes photobleaching from light irradiation
- Accumulates in tumor cells after administration of 5-aminolevulinic acid (5-ALA)
- Shows promise as a sonodynamic and photodynamic agent for various cancers, such as bladder cancer and nodular basal cell carcinoma
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