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Enzo Life Sciences Protoporphyrin IX (free acid) (1g). CAS: 553-12-8

Supplier: Enzo Life Sciences ALX430041G001

Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Appearance: Purple to dark brown solid. Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
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