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Medchemexpress LLC Protriptyline hydrochloride | 1225-55-4 | 99.75% | 5 MG
SDP

Supplier:  Medchemexpress LLC HYB09495MG

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Protriptyline hydrochloride is a potent tricyclic antidepressant (TCA) that inhibits AChE activity with an IC50 value of 0.06 mM and inhibits Aβ self-assembly. It can be used for the study of depression and Alzheimer's disease.

  • Inhibits AChE activity with an IC50 value of 0.06 mM
  • Inhibits Aβ self-assembly
  • Causes cytotoxicity in PC3 cells
  • Improves spatial learning and retention memory in STZ treated rats
  • Reduces pTau, Aβ42 and BACE-1 levels, neurodegeneration, oxidative stress, and glial activation
  • Improves p-ERK/ERK ratio and enhances BDNF and CREB levels by reducing NFκB and GFAP expression

Catalog No. 50-004-08833


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