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Medchemexpress LLC PRT062607 Hydrochloride | 1370261-97-4 | C19H24ClN9O | 100 MG
SDP

Supplier:  Medchemexpress LLC HY15323100MG

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PRT062607 (P505-15) Hydrochloride is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induces apoptosis. It also demonstrates potent antitumor activity in tumor xenograft mouse models.

  • Inhibits phosphorylation of ERK(Y204), AKT(S473), and SYK(Y352) in Ramos cells.
  • Inhibits BLNK Tyr84 phosphorylation.
  • Inhibits B cell antigen receptor-mediated B cell signaling and activation in human whole blood.
  • Inhibits Fc receptor 1-mediated induced basophil degranulation.
  • Demonstrates significant activity against various kinases including Fgr, MLK1, Yes, Flt3, PAK5, Lyn, cSRC, Lck, Pyk, and FAK.

Catalog No. 50-003-73512


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