Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000373512

Medchemexpress LLC PRT062607 Hydrochloride | 1370261-97-4 | C19H24ClN9O | 100 MG
SDP

Catalog No. 5000373512
Encompass_Preferred

PRT062607 (P505-15) Hydrochloride is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induces apoptosis. It also demonstrates potent antitumor activity in tumor xenograft mouse models.

  • Inhibits phosphorylation of ERK(Y204), AKT(S473), and SYK(Y352) in Ramos cells.
  • Inhibits BLNK Tyr84 phosphorylation.
  • Inhibits B cell antigen receptor-mediated B cell signaling and activation in human whole blood.
  • Inhibits Fc receptor 1-mediated induced basophil degranulation.
  • Demonstrates significant activity against various kinases including Fgr, MLK1, Yes, Flt3, PAK5, Lyn, cSRC, Lck, Pyk, and FAK.

Catalog No. 50-003-73512 Supplier Medchemexpress LLC Supplier No. HY15323100MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

PRT062607 (P505-15) Hydrochloride is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induces apoptosis. It also demonstrates potent antitumor activity in tumor xenograft mouse models.

  • Inhibits phosphorylation of ERK(Y204), AKT(S473), and SYK(Y352) in Ramos cells.
  • Inhibits BLNK Tyr84 phosphorylation.
  • Inhibits B cell antigen receptor-mediated B cell signaling and activation in human whole blood.
  • Inhibits Fc receptor 1-mediated induced basophil degranulation.
  • Demonstrates significant activity against various kinases including Fgr, MLK1, Yes, Flt3, PAK5, Lyn, cSRC, Lck, Pyk, and FAK.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.