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Medchemexpress LLC Prx-07034 hydrochloride | 903580-39-2 | 99.0% | C21H29Cl2N3O4S | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY14559

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PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a Ki of 4-8 nM and IC50 of 19 nM. Intended for research on enhancing working memory and cognitive flexibility, it shows significant 5-HT6 receptor selectivity (>100-fold over 68 other GPCRs, ion channels, and transporters). It also inhibits 5-HT1A, 5-HT1B, 5-HT1D, Dopamine D3, Histamine H2, and Opioid μ receptors. In vivo studies in rats demonstrated enhanced delayed spontaneous alternation and improved cognitive strategy switching.

  • Highly selective and potent 5-HT6 receptor antagonist
  • Ki of 4-8 nM and IC50 of 19 nM for 5-HT6 receptor
  • Enhances working memory and cognitive flexibility
  • >100-fold selectivity over 68 other GPCRs, ion channels, and transporters
  • Inhibits 5-HT1A, 5-HT1B, 5-HT1D, Dopamine D3, Histamine H2, and Opioid μ receptors

Catalog No. 50-003-53118


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