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Apexbio Technology LLC PSB 1114 500ug
Supplier: Apexbio Technology LLC B76490.5
PSB 1114 is a small-molecule agonist targeting the purinergic P2Y2 receptor It is designed to selectively activate the P2Y2 receptor a G protein-coupled receptor (GPCR) naturally activated by extracellular nucleotides thereby regulating downstream signaling pathways such as chloride ion secretion mucosal hydration and inflammatory responses PSB 1114 exerts its biological activity primarily through P2Y2 receptor activation It demonstrates subtype selectivity within the P2Y receptor family with an EC50 value of approximately 0 134 M for the P2Y2 receptor and exhibits lower affinity towards related subtypes Based on these pharmacological properties PSB 1114 holds research potential in studies exploring therapeutic approaches for respiratory diseases including cystic fibrosis via modulation of ion transport and mucosal hydration mechanisms mediated by P2Y2 receptor activation
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