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Selleck Chemical LLC Pseudolaric Acid A-E0249-5MG

Supplier: Selleck Chemical LLC E02495MG
Pseudolaric acid A a Hsp90 inhibitor with an IC50 of 0 60 M 2 72 M 1 36 M 2 92 M and 6 16 M in HL-60 A549 SMMC-7721 HeLa and SW480 cells respectively is the main bioactive ingredient in Pseudolarix cortex and induces cell cycle arrest at G2/M phase and promotes cell death through caspase-8/caspase-3 pathway demonstrating potent antiproliferation and anticancer activities
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