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Cayman Chemical PseudoprotodIoscIn 10mg
Supplier: Cayman Chemical 3321510 MG
A steroidal saponin; cytotoxic to A375, L929, and HeLa cancer cells (IC50s = 5.73, 5.09, and 3.32 µM, respectively); increases ERα nuclear accumulation in 3T3-L1 preadipocytes cultured in differentiation medium; inhibits LPS-induced increases in NF-κB activity in reporter assays using isolated mouse peritoneal macrophages and HUVECs; reduces atherosclerotic plaque area and inhibits increases in serum total cholesterol and triglyceride levels in ovariectomized ApoE-/- mice fed a high-cholesterol diet at 1, 2.5, and 5 mg/kg
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