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Medchemexpress LLC Pseudouridine | 1445-07-4 | 99.9% | 244.20 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY11306110MM/1ML

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Pseudouridine is an isomer of uridine, the most abundant modified nucleoside found in non-coding RNA. It plays a crucial role in fine-tuning and stabilizing regional structures in rRNA and tRNA, essential for mRNA decoding, ribosome assembly, processing, and translation. This modification provides an additional hydrogen bond donor at its non-Watson-Crick edge, giving it distinct chemical properties and maintaining its function as the 'fifth nucleotide' across all phylogenetic domains of life.

  • Most abundant modified nucleoside in non-coding RNA.
  • Essential for mRNA decoding, ribosome assembly, processing, and translation.
  • Provides an additional hydrogen bond donor.
  • Present across all phylogenetic domains of life.
  • Modified tRNA fragments may inhibit aberrant protein synthesis.
  • Stabilizes RNA and improves base stacking.

Catalog No. 50-004-35637


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