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Medchemexpress LLC Pseudouridine | 1445-07-4 | MFCD00038458 | 99.9% | 244.20 | 5 MG
Supplier: Medchemexpress LLC 5MGHY113061
Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia.
- Most abundant modified nucleoside in non-coding RNA
- Fine-tunes and stabilizes regional structures in rRNA and tRNA
- Maintains functions in mRNA decoding, ribosome assembly, processing, and translation
- Inhibits aberrant protein synthesis
- Forms additional hydrogen bonds, stabilizing RNA and improving base stacking
- Found in all three phylogenetic domains of life
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