β-Pseudouridine, MP Biomedicals™

Description

Used in initiation of translation. β-Pseudouridine, MP Biomedicals is an isomer of the nucleoside uridine, found in all species and in many classes of RNA (except mRNA). Studies suggest that it reduces radiation-induced chromosome aberrations in huma

β-Pseudouridine is formed by enzymes called Ψ synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation.

Specifications

Chemical Identifiers

• CAS: 1445-07-4
• Molecular Formula: C9H12N2O6
• Molecular Weight (g/mol): 244.20
• MDL Number: MFCD00038458
• InChI Key: PTJWIQPHWPFNBW-GBNDHIKLSA-N
• Synonym: pseudouridine, beta-pseudouridine, psi-uridine, 5-beta-d-ribofuranosyl uracil, beta-d-pseudouridine, 5-b-d-ribofuranosyl-uracil, pseudouridine c, 5-ribosyluracil, 1s-1,4-anhydro-1-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl-d-ribitol, 5-2s,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidine-2,4 1h,3h-dione
• PubChem CID: 15047
• ChEBI: CHEBI:17802
• IUPAC Name: 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-pyrimidine-2,4-dione
• SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)C1=CNC(=O)NC1=O

• Density: 1.64g/cm3
• Boiling Point: 598.4°C (760 mmHg (literature))
• Refractive Index: 1.62 (Lit.)
• Quantity: 250 mg
• Solubility Information: Soluble in water (50mg/mL, clear, colorless solution).
• Formula Weight: 244.2g/mol
• Physical Form: Powder

Safety and Handling

Recommended Storage

Store at 4°C.