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ABclonal Technology PSMC5 Rabbit pAb
SDP

Catalog No. 5000097888
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The 26S proteasome is a multicatalytic proteinase complex consisting of a 20S core and a 19S regulator. The 20S core has 4 rings of 28 subunits, with 7 alpha and 7 beta subunits in each ring. The 19S regulator contains a base with 6 ATPase and 2 non-ATPase subunits, and a lid with up to 10 non-ATPase subunits. Proteasomes are abundant in eukaryotic cells and degrade peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome processes class I MHC peptides. This gene encodes an ATPase subunit from the triple-A ATPase family, with chaperone-like activity. Besides proteasome functions, it may also be involved in transcriptional regulation by interacting with the thyroid hormone and retinoid X receptors. Two transcript variants encoding different isoforms have been identified.

Catalog No. 50-000-97888 Supplier ABclonal Technology Supplier No. A13537100UL
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The 26S proteasome is a multicatalytic proteinase complex consisting of a 20S core and a 19S regulator. The 20S core has 4 rings of 28 subunits, with 7 alpha and 7 beta subunits in each ring. The 19S regulator contains a base with 6 ATPase and 2 non-ATPase subunits, and a lid with up to 10 non-ATPase subunits. Proteasomes are abundant in eukaryotic cells and degrade peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome processes class I MHC peptides. This gene encodes an ATPase subunit from the triple-A ATPase family, with chaperone-like activity. Besides proteasome functions, it may also be involved in transcriptional regulation by interacting with the thyroid hormone and retinoid X receptors. Two transcript variants encoding different isoforms have been identified.

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