Psoralen (CAS No 66-97-7) is a natural compound classified in the research category of furocoumarins predominantly derived from plants like Psoralea corylifolia It functions primarily by intercalating with DNA and forming cross-links upon activation by ultraviolet A (UVA) light inhibiting DNA synthesis and transcription This mechanism targets nucleic acids making it a valuable tool in understanding genetic processes Common in vitro activity is observed in the nanomolar to low micromolar range reflecting its potent biological effects Psoralen s applications are vast including use in cell models to study apoptosis photochemotherapy in animal studies and drug screening for antiproliferative agents Experimental concentrations typically depend on the specific research design which allows for its flexible integration into various biomedical research protocols