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Cayman Chemical Pteryxn 50mg
SDP

Supplier:  Cayman Chemical 3032050 MG

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A peptide agonist of CaSR selective for CaSR over a panel of 33 receptors and ion channels as well as the norepinephrine transporter at 10 UM increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 0 53 UM) inhibits parathyroid secretion from primary rat parathyroid cells (EC50 0 36 UM in the presence of calcium) decreases parathyroid hormone and calcium in plasma and serum respectively in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0 3 1 and 3 mg/kg

Catalog No. 50-298-8395


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