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Apexbio Technology LLC Parathyroid hormone (1-34) (human) 52232-67-4 1mg
Supplier: Apexbio Technology LLC A11291
Parathyroid hormone (1-34) (human) is a synthetic peptide fragment corresponding to the first 34 amino acids of the endogenous human parathyroid hormone (PTH) with the amino acid sequence H2N-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-OH and a molecular formula of C181H291N55O51S2 (molecular weight 4117 72) Endogenous PTH produced by chief cells of the parathyroid glands regulates calcium homeostasis by increasing circulating calcium ions (Ca ) Mechanistically PTH binds primarily to parathyroid hormone receptors (PTH1R and PTH2R) to induce calcium release from bone enhance renal tubular reabsorption of calcium and magnesium and facilitate intestinal calcium absorption indirectly through increased active vitamin D production This peptide fragment is widely used in biomedical research to investigate calcium metabolism bone remodeling processes and related endocrinological pathways
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