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Medchemexpress LLC pTH (39-84) (human) | 90880-43-6 | 98.9% | 4984.50 | 5 MG
Supplier: Medchemexpress LLC HYP100785MG
pTH (39-84) (human) is the C-terminal fragment of parathyroid hormone (PTH). It increases apoptosis and can stimulate osteoclast formation.
- Slightly stimulates osteoclast-like cell formation at 3000 nM when used alone.
- Reduces Vitamin D-dependent osteoclast-like cell formation by 70% when co-treated with VitD in primary murine bone marrow cultures.
- Induces perinuclear redistribution of connexin 43 (Cx43) and increases apoptosis without increasing total Cx43 protein levels in PTH1R-knockout murine osteocyte-like OC cells at 1000 nM (2-16 h).
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