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Immunology Consultants Hamster (CHO) Legumain Protein - Recombinant, 0.025mg, Lyophilized
Supplier: Immunology Consultants AG650423LY
This recombinant CHO Legumain (LGMN; GenBank XP_003509181.1) is expressed in CHO‑S cells with a 6xHIS tag and purified by nickel affinity chromatography to >90% purity. Legumain appears at ~60 kDa under reducing conditions and is quantified by Bradford assay. As a lysosomal cysteine protease, Legumain can cleave asparaginyl and aspartyl bonds in therapeutic antibodies, impacting stability and efficacy. This high‑quality recombinant antigen provides a dependable standard for ELISA calibration, HCP assay development, and protease‑related risk assessment. Its CHO‑derived structure ensures biological relevance for impurity profiling and purification optimization. Ideal for teams studying protease activity, refining downstream processes, or building targeted detection tools.
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