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Medchemexpress LLC Puromycin dihydrochloride | 58-58-2 | 99.9% | 1 ML
SDP

Supplier:  Medchemexpress LLC HYB1743A10MM/1ML

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Puromycin dihydrochloride is an aminonucleoside antibiotic that inhibits protein synthesis by blocking aminoacyl-sRNA formation, leading to the accumulation of small peptides. It causes premature termination of translation by linking non-specifically to growing polypeptide chains. When used in minimal amounts, puromycin incorporation in newly synthesized proteins directly reflects the rate of mRNA translation in vitro.

  • Acts as an analog of the 3' end of aminoacyl-tRNA.
  • Inhibits protein synthesis by interfering with translation.
  • Can be used for direct evaluation of translation activity in single cells by immunofluorescence microscopy.
  • Suitable for heterogeneous populations of cells by fluorescence-activated cell sorting.

Catalog No. 50-004-11445


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