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Medchemexpress LLC Puromycin dihydrochloride | 58-58-2 | 99.9% | 1 ML

Supplier: Medchemexpress LLC HYB1743A10MM/1ML
Puromycin dihydrochloride is an aminonucleoside antibiotic that inhibits protein synthesis by blocking aminoacyl-sRNA formation, leading to the accumulation of small peptides. It causes premature termination of translation by linking non-specifically to growing polypeptide chains. When used in minimal amounts, puromycin incorporation in newly synthesized proteins directly reflects the rate of mRNA translation in vitro.
- Acts as an analog of the 3' end of aminoacyl-tRNA.
- Inhibits protein synthesis by interfering with translation.
- Can be used for direct evaluation of translation activity in single cells by immunofluorescence microscopy.
- Suitable for heterogeneous populations of cells by fluorescence-activated cell sorting.
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