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Medchemexpress LLC Purvalanol B (NG 95) | 212844-54-7 | 97.0% | 432.90 | 200 MG
Supplier: Medchemexpress LLC HY18299200MG
Purvalanol B (NG 95) is a potent, selective, reversible, and ATP-competitive inhibitor of cyclin-dependent kinases (CDK). It demonstrates significant selectivity for CDK over other protein kinases and effectively inhibits the growth of a chloroquine-resistant strain of *P. falciparum*.
- Potent, selective, reversible, and ATP-competitive inhibitor of CDK
- Inhibits cdc2-cyclin B, CDK2-cyclin A, and CDK5-p35 with IC50s of 6 nM
- Inhibits CDK2-cyclin E with an IC50 of 9 nM
- Shows selectivity for CDK over other protein kinases (IC50 > 1000 nM)
- Inhibits the growth of a chloroquine-resistant strain of *P. falciparum*
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