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Medchemexpress LLC PXS-5120A | 2125955-70-4 | 98.1% | C22H25ClFN3O4S | 10MG
Supplier: Medchemexpress LLC HY13024210MG
PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of lysyl oxidase-like enzymes LOXL2 and LOXL3, described in the medicinal chemistry literature as a mechanism-based inhibitor with anti-fibrotic activity and high selectivity for LOXL2. It is supplied for research use and has been characterized by CAS, formula, and molecular weight in supplier and public databases.
- Irreversible mechanism-based inhibitor of LOXL2 and LOXL3.
- Greater than 300-fold selectivity for LOXL2 versus LOX.
- Reported Ki ~83 nM for LOXL2 and pIC50 ≈ 8.4.
- Suitable for anti-fibrotic and LOXL biology research.
- Characterized molecular formula and molecular weight for analytical use.
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