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Medchemexpress LLC PXS-6302 hydrochloride | 2584947-79-3 | C10H11ClF3NO2S | 50 MG

Supplier: Medchemexpress LLC HY151499A50MG
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor known for its good skin penetrability, ability to reduce collagen deposition, and significant improvement of scar appearance. This compound is intended for research use only.
- Irreversible lysyl oxidase inhibitor
- Exhibits IC50s for Bovine LOX (3.7 μM), rh LOXL1 (3.4 μM), rh LOXL2 (0.4 μM), rh LOXL3 (1.5 μM), and rh LOXL4 (0.3 μM)
- Reduces collagen deposition and cross-linking in murine models of injury and fibrosis with topical application
- Significantly improves scar appearance in porcine injury models without reducing tissue strength
- Inhibits LOX and reduces crosslinking in porcine models of excisional and burn injury
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