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Apexbio Technology LLC Pyrazinamide 98-96-4 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B21225.1

Pyrazinamide is an antimycobacterial agent primarily used in the laboratory research of tuberculosis infection As a synthetic pyrazine derivative it acts by targeting mycobacterial fatty acid synthesis pathways and disrupting bacterial membrane energetics thereby exerting bactericidal activity particularly under acidic conditions Pyrazinamide is routinely employed in in vitro cell and bacterial culture studies to investigate mechanisms of tuberculosis pathogenesis drug resistance and potential combination therapies Its inhibitory effect is usually quantified in terms of IC50 values typically ranging from approximately 10 to 60 g/mL depending on experimental conditions and mycobacterial strain types
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