Corning™ PYREX™ Low-Actinic Media/Solution Bottles

Catalog No.	Capacity (Metric)	Graduations	Mouth
13-646-21	50 mL	20 to 50 mL	Narrow
13-646-20	25 mL	10 to 25 mL	Narrow
06-423-2A	100 mL	40 to 80 mL	Wide
06-423-2B	250 mL	50 to 200 mL	Wide
06-423-2C	500 mL	100 to 400 mL	Wide
06-423-2D	1 L	100 to 900 mL	Wide
06-423-2F	2000 mL	400 to 1800 mL	Wide
064232G	5000 mL	500 to 4500 mL	Wide
064232J	10 L	2000 to 9000 mL	Wide

Catalog No. 13-646-21 Supplier Corning™ Supplier No. 5139550

Description

Ideal for storing and transporting light-sensitive materials

Heavy duty bottle of low actinic glass for use when storing/transporting light sensitive materials. Includes a linerless, one-piece, autoclavable, orange polypropylene, plug-seal cap with drip-free pouring rings. Glass bead indicates full capacity line. Permanent white enamel graduations and marking spots. 

Replacement caps and pouring rings are available (catalog 1395 series).

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Specifications

• Capacity: 1.69 oz., 50 mL
• Capacity (Metric): 50 mL
• Capacity (English): 1.69 oz.
• Diameter (English): 1.8 in.
• Diameter (English) Inner Neck: 1.14 in.
• Diameter (Metric) Inner Neck: 29 mm
• Material: Borosilicate Glass
• No. per Case: 4/Cs.
• No. per Pack: 4/Pk.
• Sterility: Non-sterile
• Closure Color: Orange
• Graduations: 20 to 50 mL
• Certifications/Compliance: ASTM E438, Type I, Class A
• Mouth: Narrow
• Shape: Cylindrical
• Height (Metric): 88 mm
• Height (English): 3.4 in.
• Closure Material: Polypropylene
• Closure Size: GL 32
• Diameter (Metric): 46 mm
• Closure Type: Plug Seal

Frequently Asked Questions (FAQs)

What are the advantages of using PYREX Low Actinic Glassware?

• Reduces light transmission to protect sensitive samples
• Ensures stability and precision in experiments and long-term storage
• Durable construction for reliable use in various laboratory applications

What applications are PYREX Low Actinic Glassware suitable for?

PYREX Low Actinic Glassware is ideal for:
• Chemistry
• Biology
• Pharmaceuticals
• Photochemistry experiments
• Any process involving chemicals or substances sensitive to light in the 3,000 to 5,000 Angstrom range

Why use PYREX Low Actinic Glassware?

It is designed to reduce light transmission, particularly UV and visible wavelengths, protecting light-sensitive samples such as chemicals, reagents, and biological materials from degradation caused by light exposure. This minimizes light-induced reactions, ensuring the stability and integrity of stored or processed substances.

What is PYREX Low Actinic Glassware made of?

PYREX Low Actinic Labware is made from Type I, Class A borosilicate glass with copper replacing the sodium in the glass composition structure, ensuring durability equal to the base glass.

What are the key features of PYREX Low Actinic Glassware?

• Non-pyrogenic
• Human DNA-free
• PCR inhibitor-free
• RNase-/DNase-free
• Made with USP Class VI Polypropylene (for plastic components)
• Provides protection for materials sensitive to light

How can I increase the lifespan of my PYREX and PYREXPLUS bottles?

Proper care includes:
• Avoiding mechanical damage (e.g., scratches or chips)
• Preventing thermal shock
• Following recommended cleaning and sterilization techniques

How should I clean PYREX bottles?

1. Wash bottles promptly after use, or soak them in water if immediate cleaning isn’t possible
2. Sterilize bottles contaminated with biological materials before cleaning
3. Use detergent and rinse thoroughly with tap water, followed by deionized or distilled water
4. For new bottles used in cell culture, soak in a 1% hydrochloric or nitric acid solution before washing

What precautions should I take when autoclaving PYREX bottles?

• Do not tighten caps immediately after autoclaving to prevent vacuum breakage, except for vented caps (e.g., 1395-45LTMC)
• Replace vented caps after 3-5 autoclave cycles or if the membrane is damaged

Can I use PYREX bottles with bottle-top filter units?

Do not use bottle-top filter units with reagent bottles larger than 1000 mL or laboratory bottles larger than 2000 mL.

Are PYREX bottles suitable for vacuum or pressure applications?

PYREX bottles larger than 2000 mL are not recommended for vacuum applications. Additionally, 1396 and 1397 series bottles are not designed for vacuum use.

What safety precautions should I take when using PYREX bottles?

Follow these safety guidelines:
• Avoid using scratched, cracked, or nicked glassware
• Do not expose bottles to direct heat, such as a flame or hot plate
• Prevent thermal shock by avoiding rapid temperature changes (e.g., placing hot bottles on cold surfaces)
• Do not refrigerate below -20°C or expose PYREXPLUS bottles to temperatures above 80°C

Are vented caps available, and what are they used for?

Yes, vented caps with a 0.22 µm PTFE membrane allow automatic gas exchange during autoclaving. They are suitable for use with bottle sizes ranging from 100 mL to 2000 mL.

Can the caps withstand high temperatures?

The standard orange polypropylene caps can withstand up to 140°C. Optional red PBT caps with PTFE-coated liners are available for applications requiring temperatures up to 180°C.

What types of caps are available for PYREX bottles?

A variety of optional closures are available, including:
• Plug seal, GL45 and GLS80 color-coded caps for sorting and identification
• High-temperature PBT caps with PTFE-coated liners, ETFE copolymer rings, or silicone septa (suitable for dry heat sterilization up to 180°C)
• Vented GL45 caps with 0.22 µm PTFE hydrophobic membranes for automatic gas exchange
• Open-top PBT caps in GL25, GL32, and GL45 sizes
• Silicone or PTFE-faced silicone septa for open-top caps

What material are PYREX bottles made of?

PYREX bottles are made from Type I, Class A borosilicate glass, which is chemically resistant and has low thermal expansion. They come with clear polypropylene pouring rings and caps and are fully autoclavable.

What are PYREX and PYREXPLUS reusable laboratory bottles used for?

PYREX bottles are heavy-duty storage vessels designed for reagents, sterile tissue culture media, biological fluids, aqueous and nonaqueous solutions. PYREXPLUS bottles have a PVC coating for added protection, and Low Actinic bottles are available for light-sensitive materials.