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Medchemexpress LLC Pyridine, 4-[4-(6-methoxy-2-naphthalenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl] | 948557-43-5 | 99.8% | 439.53 g/mol | C26H21N3O2S | 10 MG
SDP

Supplier:  Medchemexpress LLC HY10055610MG

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Tie2 kinase inhibitor 1 is a potent, selective small-molecule inhibitor of the Tie2 receptor tyrosine kinase with reported in vitro Tie2 IC50 = 250 nM and cellular activity (cell IC50 ≈ 232 nM). It is supplied as a high-purity solid for preclinical research into angiogenesis and anticancer mechanisms.

  • Potent Tie2 inhibition (IC50 250 nM).
  • Demonstrated cellular activity (cell IC50 ≈ 232 nM).
  • High purity (99.8%).
  • Soluble in DMSO (≈17.86 mg/mL) for in vitro use.
  • In vivo formulation options reported at ≥1.79 mg/mL for dosing studies.
  • Stable when stored under recommended conditions for long-term use.

Catalog No. 50-002-12394


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