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Medchemexpress LLC Pyridinium, 3-carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt (triethylamine) | 321-02-8 | 99.9% | 25 MG

Supplier: Medchemexpress LLC 25MGHY128700A
Nicotinic acid mononucleotide (NAM) acts as a SARM1 inhibitor and an intermediate in NAD+ biosynthesis, with an IC50 value of 93.3 μM against SARM1. It is intended for research use only.
- Acts as an allosteric SARM1 inhibitor.
- Plays a role in the biosynthesis of NAD+.
- Exerts protective effects on axons and delays axonal degeneration.
- Increases NAD+ levels in the body.
- Boosts the activity of Sirt1.
- Improves myocardial capillary density and alleviates myocardial fibrosis.
- Reverses diabetic cardiomyopathy in diabetic mice by increasing myocardial NAD+ levels.
- Applicable for research related to cancer, multiple sclerosis, diabetic cardiomyopathy, neurodegenerative diseases, and Huntington's disease.
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