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Medchemexpress LLC Pyridinium, 3-carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt (triethylamine) | 321-02-8 | 99.9% | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY128700A

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Nicotinic acid mononucleotide (NAM) acts as a SARM1 inhibitor and an intermediate in NAD+ biosynthesis, with an IC50 value of 93.3 μM against SARM1. It is intended for research use only.

  • Acts as an allosteric SARM1 inhibitor.
  • Plays a role in the biosynthesis of NAD+.
  • Exerts protective effects on axons and delays axonal degeneration.
  • Increases NAD+ levels in the body.
  • Boosts the activity of Sirt1.
  • Improves myocardial capillary density and alleviates myocardial fibrosis.
  • Reverses diabetic cardiomyopathy in diabetic mice by increasing myocardial NAD+ levels.
  • Applicable for research related to cancer, multiple sclerosis, diabetic cardiomyopathy, neurodegenerative diseases, and Huntington's disease.

Catalog No. 50-003-42380


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