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AdipoGen Pyridomycin
Supplier: AdipoGen BVT0455M001
Chemical. CAS 18791-21-4. Formula C27H32N4O8. MW 540.6. Isolated from Streptomyces sp. Cyclodepsipeptide antibiotic. Unusual 12-membered macrocyclic depsipeptide comprises three unique subunits incorporating two substituted pyridines. Potent antitubercular agent. Inhibitor of NADH-dependent enoyl Acyl-Carrier-Protein reductase InhA, preventing mycolic acid synthesis in M. tuberculosis. Shown to be active against isoniazid-resistant mycobacteria.
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