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Medchemexpress LLC HY-14435 100mg , Pyridone 6 CMP 6;JAK Inhibitor CAS:457081-03-7 Purity:98%
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Supplier:  Medchemexpress LLC HY14435100MG

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Medchemexpress, HY-14435 100mg Pyridone 6 CMP 6;JAK Inhibitor CAS:457081-03-7 Formula:C18H16FN3O IC50: 1 nM (JAK2), 5 nM (JAK3), 15 nM (JAK1), 1 nM (TYK2) Purity:98% Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC 50 s of 1 nM for JAK2 and TYK2 , 5 nM for JAK3 , and 15 nM for JAK1 , while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Catalog No. 50-149-3564


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