Pyrilamine maleate

Description

Selective inverse agonist for the H-1 histamine receptor | CAS: 59-33-6 | C21H27N3O5 | 401.46 g/mol

Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.

Solubility
Soluble in water at 100mg/ml

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

• CAS: 59-33-6
• Color: White
• Molecular Formula: C21H27N3O5
• Quantity: 25 g
• MDL Number: MFCD00069333
• Merck Index: 14,7984
• Synonym: pyrilamine maleate, mepyramine maleate, anisopyradamine, histosol, minihist, diaminide maleate, paraminyl maleate, antihist, histatex, histine
• Solubility Information: Soluble in water at 100mg/ml
• InChI Key: JXYWFNAQESKDNC-BTJKTKAUSA-N
• SMILES: OC(=O)\C=C/C(O)=O.COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1
• IUPAC Name: (2Z)-but-2-enedioic acid; N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
• Molecular Weight (g/mol): 401.46
• PubChem CID: 5284451
• Formula Weight: 401.46
• Physical Form: Powder
• Chemical Name or Material: Pyrilamine maleate

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	GHS P Statement P261-P280-P305+P351+P338-P304+P340-P405-P501a Avoid breathing dust/fume/gas/mist/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber	200-422-7
RTECSNumber	UT1225000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only