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Medchemexpress LLC Pyrimido[4,5-d]pyrimidin-2(1H)-one, 7-[[2-methoxy-4-(1-methyl-4-piperidinyl)phenyl]amino]- | 1936529-65-5 | 99.8% | 600.11 | C32H34ClN7O3 | 250 MG
SDP

Supplier:  Medchemexpress LLC HY101147250MG

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YKL-05-099 is a small-molecule salt-inducible kinase (SIK) inhibitor used as a research tool in biochemical and cell-based studies. It exhibits high potency for SIK1 and SIK3, with reported IC50 values in the low nanomolar range, and is applied for kinase assays, signaling investigations, and target validation. The compound has a molecular weight of 600.11 and a reported purity of 99.76%.

  • Potent inhibition of SIK1 and SIK3 (IC50 ≈ 10 and 30 nM, respectively).
  • Moderate activity against SIK2 (IC50 ≈ 40 nM).
  • High chemical purity (99.76%).
  • Suitable for biochemical kinase assays and cell-based signaling studies.
  • Provided as a solid research compound for laboratory use.

Catalog No. 50-002-11456


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