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Lonza Walkersville PyroGene Recombinant Factor C Endpoint Fluorescent Assay

Catalog No. NC1031961
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The PyroGene Recombinant Factor C Assay is the evolution of endotoxin detection testing. Lonza scientists have developed a recombinant form of Factor C, the first component in the horseshoe crab clotting cascade activated by endotoxin. Recombinant Factor C (rFC) is activated by endotoxin binding, and the active enzyme then cleaves a synthetic substrate, resulting in the generation of a fluorogenic compound. PyroGene rFC works through a single enzymatic step compared to the multiple step enzymatic process necessary for LAL assays.Benefits:Sensitivity range from 0.005 to 5 EU/mlHigher endotoxin specificity through the elimination of false positive glucan reactionsLess lot-to-lot variabilitySecurity of supplyFDA acknowledged alternative to LALApplications:Water testingTesting plant-based materialContent:2 x 96 tests/vialrFC enzyme solution2 x 6 mL/vial fluorogenic substrate2 x 5 mL/vial rFC assay buffer2 vials endotoxin2 x 30 mL/vial LAL Reagent Water

Catalog No. NC1031961 Supplier Lonza Walkersville Supplier No. 50658U
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The PyroGene Recombinant Factor C Assay is the evolution of endotoxin detection testing. Lonza scientists have developed a recombinant form of Factor C, the first component in the horseshoe crab clotting cascade activated by endotoxin. Recombinant Factor C (rFC) is activated by endotoxin binding, and the active enzyme then cleaves a synthetic substrate, resulting in the generation of a fluorogenic compound. PyroGene rFC works through a single enzymatic step compared to the multiple step enzymatic process necessary for LAL assays.Benefits:Sensitivity range from 0.005 to 5 EU/mlHigher endotoxin specificity through the elimination of false positive glucan reactionsLess lot-to-lot variabilitySecurity of supplyFDA acknowledged alternative to LALApplications:Water testingTesting plant-based materialContent:2 x 96 tests/vialrFC enzyme solution2 x 6 mL/vial fluorogenic substrate2 x 5 mL/vial rFC assay buffer2 vials endotoxin2 x 30 mL/vial LAL Reagent Water

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