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Cayman Chemical Pyruvate asy Buffer10X 10mL
Supplier: Cayman Chemical 70047110 ML
A CB2 receptor agonist (Ki 7.6 nM for the mouse receptor) selective for CB2 receptors over CB1 receptors (Ki 900 nM for the mouse receptor) induces the CB2 receptor-dependent phosphorylation of ERK1/2 in HL-60 cancer cells at 5 to 100 nM increases the mechanical threshold force to paw withdrawal and the latency to paw withdrawal from a radiant heat stimulus in a mouse model of SNI-induced neuropathic pain at 4 mg/kg per day inhibits SNI-induced increases in the number of activated spinal microglia and spinal astrocytes in the same mice
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