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Cayman Chemical Q94hydrochlorIde hydrate 10mg

Supplier: Cayman Chemical 3285710 MG
A Gαq signaling-biased PAR1 antagonist (IC50 = 916 nM); inhibits thrombin- or a PAR1-activating peptide-induced increases in intracellular calcium mobilization in HMEC-1 cells at 1 and 10 μM; decreases albuminuria in a doxorubicin-induced mouse model of nephropathy at 5 mg/kg per day
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