Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000061550

Apexbio Technology LLC QNZ (EVP4593) 545380-34-5 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC A42175.1

Encompass_Preferred

QNZ (EVP4593 CAS number 545380-34-5) is a quinazoline-derived small molecule inhibitor of the NF- B signaling pathway Originally identified using a luciferase reporter assay in human Jurkat T cells QNZ effectively suppresses PMA/PHA-induced NF- B transcriptional activation (IC50 11 nM) and TNF- production (IC50 7 nM) Additionally QNZ demonstrates anti-inflammatory properties reducing edema formation in a carrageenan-induced rat paw swelling model In Huntington s disease research QNZ improved motor performance in transgenic fly models without toxicity suggesting potential neuroprotective applications

Catalog No. 50-000-61550


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.