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Medchemexpress LLC Queuine dihydrochloride | 86496-18-6 | 350.20 | 50 MG

Supplier: Medchemexpress LLC HYN10574A50MG
Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT), incorporated into eukaryotic tRNA to promote modification. Its deficiency enhances aerobic glycolysis, inhibits oxidative phosphorylation, and promotes Warburg metabolism. It is useful for autoimmune diseases and cancer metabolic regulation and is for research use only.
- Selective substrate for tRNA guanine transglycosylase.
- Promotes tRNA modification in eukaryotic cells.
- Impacts mitochondrial function and Warburg metabolism.
- Deficiency linked to enhanced glycolysis and inhibited oxidative phosphorylation.
- Potential for autoimmune disease and cancer metabolic research.
- Reduces lactate dehydrogenase activity and lactate production.
- Natural TGT substrate, replacing guanine (G34) in tRNA.
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