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Medchemexpress LLC Quinacrine hydrochloride hydrate | 6151-30-0 | 98.2% | 508.91 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY13735B100MG

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Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent with anticancer effects both in vitro and in vivo. It suppresses NF-κB and activates p53 signaling, which results in the induction of apoptosis.

  • Antimalarial agent
  • Possesses anticancer effects both in vitro and in vivo
  • Suppresses NF-κB and activates p53 signaling
  • Induces apoptosis
  • Inhibits growth and induces apoptosis in SGC-7901 cells
  • Increases proapoptotic proteins (cytochrome c, Bax, p53) and decreases antiapoptotic protein (Bcl-2)
  • Suppresses circulating blast cells and increases survival time in an AML-PS model
  • Does not decrease body weight in treated animals

Catalog No. 50-003-49627


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