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Medchemexpress LLC Quinine | 130-95-0 | 99.8% | 10 G
Supplier: Medchemexpress LLC HYD014310G
Quinine is an alkaloid derived from the bark of the cinchona tree, acting as an anti-malaria agent. It functions as a potassium channel inhibitor, specifically inhibiting WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM. It is for research use only and not sold to patients.
- Anti-malaria agent
- Potassium channel inhibitor (inhibits WT mouse Slo3 (KCa5.1) channel currents with an IC50 of 169 μM)
- Inhibits DENV virus replication in HepG2 cells
- Reduces DENV-positive cells in a dose-dependent manner
- Shows tumor-suppressing effects on skin cancer in Swiss albino mice
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