Quinine monohydrochloride dihydrate, 99% (total base), may contain up to 10% Dihydroquinine

Description

CAS: 6119-47-7 | C20H29ClN2O4 | 396.91 g/mol

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

Solubility
Sparingly soluble in water.(0.26 g/L) (25°C),

Notes
Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 6119-47-7
• Molecular Formula: C20H29ClN2O4
• Molecular Weight (g/mol): 396.91
• MDL Number: MFCD00151248
• InChI Key: MPQKYZPYCSTMEI-VQYSEXPNNA-N
• Synonym: quinine hcl dihydrate
• PubChem CID: 124080947
• IUPAC Name: (R)-[(2S,4S,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;dihydrate;hydrochloride
• SMILES: O.O.Cl.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C

• Quantity: 50 g
• Beilstein: 6112655
• Sensitivity: Light sensitive
• Merck Index: 14,8061
• Solubility Information: Sparingly soluble in water.(0.26g/L) (25°C),
• Optical Rotation: −246° (c=2 in 0.1M HCl)
• Formula Weight: 396.91 (360.88 Anhydrous)
• Percent Purity: 99%
• Assay: (total base), may contain up to 10% Dihydroquinine
• Chemical Name or Material: Quinine monohydrochloride dihydrate

Safety and Handling

Hazard Category	H302-H317-H335
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c
EINECSNumber	205-001-1
RTECSNumber	GD2947000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only