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Apexbio Technology LLC Quisinostat dihydrochloride 875320-31-3 5mg
Supplier: Apexbio Technology LLC A46105
Quisinostat dihydrochloride (CAS 875320-31-3) also known as JNJ-26481585 dihydrochloride is an orally bioavailable pan-histone deacetylase (HDAC) inhibitor It potently suppresses the enzymatic activity of several HDAC isoforms including HDAC1 (IC50 0 11 nM) HDAC2 (IC50 0 33 nM) HDAC4 (IC50 0 64 nM) HDAC10 (IC50 0 46 nM) and HDAC11 (IC50 0 37 nM) By interfering with histone deacetylation Quisinostat dihydrochloride induces apoptosis and cell cycle arrest in tumor cells This compound is widely utilized in studies addressing tumor biology and epigenetic regulation
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