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Medchemexpress LLC Quisinostat (dihydrochloride) | 875320-31-3 | C21H28Cl2N6O2 | 5 MG
Supplier: Medchemexpress LLC HY15433A5MG
Quisinostat dihydrochloride is an orally active, potent pan-HDAC inhibitor with IC50s as low as 0.11 nM for HDAC1. This compound exhibits broad-spectrum antitumoral activity and can induce autophagy in neuroblastoma cells. It is intended for research use only.
- Orally active, potent pan-HDAC inhibitor
- Exhibits broad-spectrum antitumoral activity
- Induces autophagy in neuroblastoma cells
- Inhibits HDAC isozymes in vitro
- Shows broad-spectrum antiproliferative activity against cancer cell lines
- Induces apoptosis
- Induces H3 and H4 acetylation in A2780 ovarian carcinoma cells
- Inhibits growth of pre-established HCT116 colon xenografts in vivo
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